Mario Garrett Juarez
Development of a Simulation Framework and Experimental Setup for Improved Temperature Monitoring during Microwave Hyperthermia Treatments.
Rel. Giuseppe Vecchi, Rossella Gaffoglio, Giorgio Giordanengo, Marcello Zucchi, Giuseppe Musacchio Adorisio. Politecnico di Torino, Master of science program in Mechatronic Engineering, 2023
Abstract
Hyperthermia is a form of medical therapy, often used in cancer treatments, that involves the heating of tumor cells in the body via non-ionizing radiation. It is an adjuvant therapy that is used in conjunction with chemotherapy and/or radiotherapy to enhance their effectiveness and overall success rate. Hyperthermia can supplement the aforementioned therapies by shrinking the tumor cells or further sensitizing them to microwave radiation, as well as by augmenting their drug absorption levels. A successful therapy treatment is contingent on sufficiently and accurately heating the target region, generally in the range of 40-44°C, without harming the surrounding healthy tissues. In clinical practice, the heating can be administered using several different methods including local, regional, and whole-body hyperthermia.
In the case of this study, the heating was administered locally to a neck phantom designed to replicate the electrical properties of the human muscle, as described in existing literature, with a target sphere inserted to reproduce the presence of a tumor mass
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