Adriano Scarano
Development of CFD models for simulating stem cell cultivation bioreactors.
Rel. Daniele Marchisio, Antonio Buffo, Marco Vanni. Politecnico di Torino, Master of science program in Chemical And Sustainable Processes Engineering, 2023
Abstract
This thesis focuses on the simulation and modeling of flow, mixing, and transport in bioreactors using computational fluid dynamics (CFD), specifically in the context of bioreactors for the proliferation and specialization of stem cells for the production of cultivated meat. Conventional meat production is associated with various problems, including fatal infections, greenhouse gas emissions, land and water consumption, waste production, and antibiotic resistance. As a sustainable and ethical alternative, cultivated meat has gained attention. Plant-based products and cultured meat offer alternatives to conventional meat production, with cultured meat being produced through biotechnological processes in a laboratory. Stirred tank bioreactors are commonly used for both stem cell proliferation and specialization, and they play a crucial role in achieving scalable and economical cultured meat production.
To assess the advantages of cultured meat, its environmental impacts are compared to those of conventional meat production
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