Bone substitution is the second most frequent tissue transplantation worldwide. However, some drawbacks induced by the surgical operations may arise. An inflammation of the tissues surrounding the fracture may take place. This increase in the acidity level in the environment may provoke cells death and subsequent patient pain. Moreover, there is a relation between the biomechanics and biological environment. Depending on the stability of the implant, a faster or slower bone healing will occur, with a trade-off on the mechanical properties of the formed bone. Hence a study on a biocompatible, biodegradable and wireless pH and strain sensor has been performed in this project.