The aim of this Master Thesis is to develop a biomimetic nanosystem acting as a TrojaNanoHorse (TNH) with drug delivery capabilities and specifically targeted against Multiple Myeloma. In recent years, nanomedicine is providing innovative therapeutic approaches in treatment of cancer diseases, thanks to small size devices allowing an easy interaction with cells and biomolecules. In this Thesis the investigated material is Mesoporous Silica, which has gained an important role in biomedical applications due to its biocompatibility, resistance to biodegradation and high drug uploading capacity. A template-assisted sol-gel self-assembly process allowed to synthetize Mesoporous Silica Nanoparticles (MSNs) with a diameter of 40-50 nm, mesopores with cylindrical shape and uniform size (3-4 nm), and high specific surface area (~1000 m2/g).