As part of the development of ESA’s Earth Explorer 11 mission, the Politecnico di Torino has contributed to the design of WIVERN (WInd VElocity Radar Nephoscope), a future Earth observation mission aiming at characterizing global winds, clouds and precipitation by employing a fast-rotating, conically scanning Doppler radar antenna. In this work the primary focus is on the line-of-sigh (LOS) Doppler relative velocity measurement errors, induced by the spacecraft Attitude Determination and Control System (ADCS). The estimation of the misalignment of the antenna pointing is critical, as errors in its determination directly affect the accuracy of the observed wind, as even small angles lead to relative velocity errors along the boresight due to the high orbital speed of the satellite.