The skin has sophisticated ways of healing quickly and efficiently. Nevertheless, certain individuals' cellular responses can compromise the healing process itself, hindering or slowing it down. Failure to heal wounds - either partially or completely - is often linked to elderly age or certain diseases, such as diabetes. These factors are among the main contributors to the development of chronic wounds, i.e., wounds that, despite having been treated adequately, show little or no sign of healing, resulting in abnormal scar formation and an increased susceptibility to infection. These wounds affect millions of people worldwide and many of these remain refractory to current treatments, representing a major socio-economic burden.