As the World Health Organization estimates, around 18 million of people die from Cardiovascular Diseases every year, making them the leading cause of mortality globally. Early CVD diagnosis and treatment can significantly minimize the risk of premature death and ensure patients a normal life. Among the several potential predictors, arterial stiffness has been shown to be a valuable indicator for assessing cardiovascular risk and is closely related to Pulse Wave Velocity (PWV). The term "Pulse Wave Velocity" refers to the rate at which the pressure wave within the arteries propagates, and it is typically assessed between the carotid and femoral sites.