Bone can be affected by tumours, thus being subjected to alteration of its physiological structure with possible negative impact on its mechanical resistance. Brachytherapy has proven to be a very advantageous technique to destroy cancer because it allows a high dose of radiation to be safely delivered into the tumour, minimizing the damage to adjacent healthy tissue. Bioactive glass (BG) scaffolds are particularly interesting devices for brachytherapy due to their ability to carry out the therapeutic action in situ and support bone tissue ingrowth after the treatment. One of the most popular techniques for producing BG scaffolds is the foam replica method, which allows obtaining highly porous and interconnected 3D bone-like scaffolds.