World Health Organization (WHO) recognizes diabetes as one major health issue due to its severe complications and steadily increasing prevalence. Blood glucose oscillation related to diabetes can lead to severe acute and chronic conditions. While type 2 diabetes can be prevented with appropriate lifestyle choices, type 1 diabetes can not be prevented, and patients affected by this disease need a plan to integrate their insulin deficiency. Pharmacological therapy is extremely effective but imposes to the patient to be strictly adherent to a fixed schedule for food intake and physical activity. To improve patient quality of life and to reduce dangerous oscillation of the sugar level in the blood, researchers and industry are developing forecasting methods able to predict future values of the blood glucose level.