This thesis is part of a larger project, called MITOR (a collaboration between Politecnico di Torino (POLITO), Massachusetts Institute of Technology (MIT) and Spaulding Rehabilitation Hospital’s Motion Analysis Laboratory (an affiliate of Harvard Medical School)). This project aims to develop a wearable, wireless, low-power surface ElectroMyoGraphy (sEMG) acquisition system for long-term monitoring of muscle synergies and diagnostic motor rehabilitation. The system’s hardware specification was defined specifically for sEMG acquisition channels. Where the resulting signals are stored locally on a microSD card. The circuit diagrams were drawn referencing the schematics of the previous version of the MITOR system. In this revision, the most significant changes from the previous MITOR is an upgraded microcontroller and additional components in the acquisition channel (so the board can detect Threshold Crossing (TC) signals).